She's been compared to Steve Jobs. She's part of the new Time 100 list. Her mission - blood testing revolution.
CBS - Do you own a TV? "No."
CBS - Why not? "I work all the time, from the time I wake up, til I go to sleep every day."
At 19, she dropped out of Stanford. With a little tuition money and a lot of ideas. Now at 31 she has what many strive for - to be the youngest billionaire in the world.
CBS - Is that heady?
EH - It's not what matters, what matters is how well we do in changing the world, that's why I work, why I love what I'm doing.
What Holmes is doing is running Theranos, the biotech she founded in 2003.
She's either in a black turtleneck or a white lab coat.
She markets Theranos as a faster, cheaper alternative to a process that hasn't changed in decades.
EH: We created these tiny tubes, Nanotainers, and replace the big traditional tubes.
Theranos has a partnership with Walgreens to build thousands of wellness centers. Each offers a menu of blood tests, cancer to cholesterol, direct to consumers, and half of Medicare prices.
Some say, That's not enough blood.
EH: Every time you create something new, there should be questions. That means you've done something transformative.
When can I get this in Washington or New York?
EH: That's underway.
EH: That's underway.
Little is known about how Theranos tests work, so there's concern about putting this in patients and doctors hands.
It's a really important area. Traditionally, you need a doctor's order for a code on a lab form. But drop the price low, and preventive testing becomes possible.
CBS - You're on magazines, transforming healthcare. Where is the revolution?
EH - "It's making it personal, making it possible, cancer, child, elderly, getting around a traditional blood draw is a big deal."
EH - "It's making it personal, making it possible, cancer, child, elderly, getting around a traditional blood draw is a big deal."
Holmes is a real, rare example of what perseverance makes possible.
EH - "When I was little, I wrote a letter to my Dad, I was exciting about moving to Texas which I thought was big on science. I was 9. I grew up in a family of people who wanted to make a difference."
She hasn't wasted time, the youngest member ever of the Horatio Alger association - and the only woman among the older white men.
EH - What's wonderful is that young girls can see this and connect. Living proof that dreams are possible.
Where's there's a glass ceiling, there's an iron woman right behind it.
She has the most impressive board of any startup, Kissinger, Schultz. Kissinger says she has an iron will.
CBS staff: Why did she do this? She has an aversion to needles. Someone in her family had cancer.