HBR Publishes Case Study, Interview about Adaptive Trials

• Harvard Business School has published a 26-page case study about Adaptive Trials, download for $9, here.    
• Read an interview with the author, here.

The interview is from Harvard's business school case study podcast series.   The case is about GBM-AGILE, which starting as an ad hoc working group to make a blueprint for adaptive studies in GBM.   The case study is about converting the blueprint from the drawing board to a real world funded study.

For a different perspective on GBM Agile see these two links:

http://clincancerres.aacrjournals.org/content/24/4/737

https://www.nfcr.org/focus-areas/gbm-agile/

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I recently pulled up a few new review articles on umbrella and basket and adaptive trials.

Open Access, see Savoia 2017, Clin Sci 131:2671 [view is general but focus is cardiology], here:

https://www.ncbi.nlm.nih.gov/pubmed/29109301

...Not open access, but sound good:

Renfro 2017, Ann Oncol 28:34, Statistical Controversies... [in such trials],  

https://www.ncbi.nlm.nih.gov/pubmed/28177494

Simon 2017, Clin Pharm Ther 102:934, Critical review... [of such trial designs], 

https://www.ncbi.nlm.nih.gov/pubmed/28795401   

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See also Simon 2017 in Ann Intern Med, 165:270, Adaptive oncology trials...

https://www.ncbi.nlm.nih.gov/pubmed/27214515   

See also Renfro 2017, Cancer Lett, 387:121, Precision oncology: new era of trials...

https://www.ncbi.nlm.nih.gov/pubmed/26987624https://www.ncbi.nlm.nih.gov/pubmed/26987624

See also Renfro 2016, Cancer Treat Rev 43:74, Clinical trial designs incorporating predictive biomarkers...

https://www.ncbi.nlm.nih.gov/pubmed/26827695

See also Beckman et al. 2016, Clin Pharm Ther 100:617, Adaptive dsign for confirmatory basket trial...

https://www.ncbi.nlm.nih.gov/pubmed/27509351