Emerging Data on COVID Sequencing

https://www.biorxiv.org/content/10.1101/2020.04.21.050633v1.full.pdf

Rapid SARS CoV 2 WGS for informed public health decision-making in the Netherlands.  Munnink et al. 

The timely generation of whole genome sequences combined with epidemiological investigations facilitated early decision making in an attempt to control local transmission of SARS-CoV-2 in the Netherlands.

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https://www.biorxiv.org/content/10.1101/2020.04.25.061499v1.full.pdf

A rapid, low cost and highly sensitive SARS CoV 2 diagnostic based on  whole genome sequencing.  St Hilaire et al. [Baylor, Rice, Stanford, Shanghai]

 Using POLAR, a single person can process 192 samples over the course of an 8-hour experiment, at a cost of ~$30/patient, enabling a 24-hour turnaround with sequencing and data analysis time included. Further testing and refinement will likely enable greater enhancements in the sensitivity of the above approach.

95% sensitive at 84 genomes/ml, better than other Dx methods.