Negative PGx Real World Study

Mayo Clinic did a study whether patients with more atypical PGx genes (which presumably weren't being managed) had more hospital or ER visits than "normal" PGx profiles.

The answer was no.

Takahashi et al

https://www.dovepress.com/no-association-between-pharmacogenomics-variants-and-hospital-and-emer-peer-reviewed-article-PGPM

No Association Between Pharmacogenomics Variants and Hospital and Emergency Department Utilization: A Mayo Clinic Biobank Retrospective Study

There was a response from Youssef Roman at VCU noting the study was observational and not decisive.

https://www.dovepress.com/pathway-to-ascertain-the-role-of-pharmacogenomics-in-healthcare-utiliz-peer-reviewed-article-PGPM

Pathway to Ascertain the Role of Pharmacogenomics in Healthcare Utilization Outcomes [Letter]