COVID Mortality, Montreal Hospital, 1H2020

It's easy to forget how grim early COVID results were.

Here's a paper on mortality in a Montreal hospital cohort in March-August 2020.  Overall mortality was 30%.    The paper studies obesity; every 10 units of BMI more than doubled mortality.

https://www.nature.com/articles/s41366-021-00938-8

Methods

We conducted a retrospective cohort study in a tertiary academic center located in Montréal between March and August 2020. We included all consecutive adult patients admitted to the ICU for COVID-19-confirmed respiratory disease. Our main outcome was hospital mortality. We estimated the association between obesity, using the body mass index as a continuous variable, and hospital survival by fitting a multivariable Cox proportional hazards model.

Results

We included 94 patients. Median [q1, q3] body mass index (BMI) was 29 [26–32] kg/m2 and 37% of patients were obese (defined as BMI > 30 kg/m2). Hospital mortality for the entire cohort was 33%. BMI was significantly associated with hospital mortality (hazard ratio [HR] = 2.49 per 10 units BMI; 95% CI, from 1.69 to 3.70; p < 0.001) even after adjustment for sex, age and obesity-related comorbidities (adjusted HR = 3.50; 95% CI from 2.03 to 6.02; p < 0.001).

• Article
• Published: 25 August 2021

Epidemiology and Population Health

Association between obesity and hospital mortality in critical COVID-19: a retrospective cohort study

• Guillaume Plourde, 
• Emanuel Fournier-Ross, 
• Hubert Tessier-Grenier, 
• Louis-Antoine Mullie, 
• Michaël Chassé & 
• François Martin Carrier 

International Journal of Obesity volume 45, pages2617–2622 (2021)Cite this article