Four articles on PD

 

Bibliography (AMA Style)

1. Martinez-Valbuena I, Tartaglia MC, Kovacs GG, Lang AE. Copathology in Atypical Parkinsonism—The Rule Rather Than the Exception? JAMA Neurol. Published online June 9, 2025. doi:10.1001/jamaneurol.2025.1630.

Emphasizes the importance of aSYN then focuses on the need for 4-repeat-tau markets also in SAA.

1. Vaillancourt DE, Barmpoutis A, Wu SS, et al. Automated Imaging Differentiation for Parkinsonism. JAMA Neurol. 2025;82(5):495–505. doi:10.1001/jamaneurol.2025.0112.

2. Hswen Y, Anderer S. A Large Proportion of Parkinson Disease Diagnoses Are Wrong—Here’s How AI Could Help. JAMA. Published online June 13, 2025. https://jamanetwork.com/journals/jama/fullarticle/10.1001/jama.2025.3276

Op ed and original article on independent AI based MRI readings for neuro diseases.

1. Vieten M. Forget the Tremor: These Symptoms Come First in Parkinson’s. Medscape Medical News. Published June 10, 2025. https://www.medscape.com/viewarticle/forget-tremor-these-symptoms-come-first-parkinsons-2025a1000fj1

Updates on early DX and range of symptoms.  Does not focus on biomarkers as his points are that some symptom clusters - anosmia and REM behavior disorder - are nearly pathognomic.

Some of the points were made in a pivotal 2006 or 2008 article by Langson, PD, where parkinsonism (per se) is tip of the iceberg.